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Mar 26, 2012

PAPER OF THE WEEK

The diagnosis of hypertrophic cardiomyopathy (HCM) by cardiovascular magnetic resonance

J Cardiovasc Magn Reson 2012;14:17.

Dr. Noureldin, our dear Brazilian friend Marcelo Nacif and cols in their review, provide an overview of the clinical, pathological and imaging features relevant to understanding the diagnosis of HCM. They concluded that CMR appears to be highly relevant in the clinical as well as research evaluation of patients with overt as well as pre-clinical HCM. Late enhancement after gadolinium administration allows tissue characterization of myocardial fibrosis. The method may potentially identify HCM patients at greatest risk for adverse cardiac events. CMR evaluation of HCM mutation carriers in an early stage of disease has yet to be extensively evaluated, but represents a promising method for exploring the inter-relationship between functional, morphologic and tissue abnormalities in HCM.