PAPER OF THE WEEK

Effect of Deferiprone or Deferoxamine on Right Ventricular Function in Thalassemia Major Patients with Myocardial Iron Overload (JCMR 2011, 13:34)
Dr. G. Smith from Dr. Pennell's group, studied Thalassaemia major patients and made a retrospective analysis of a prospective randomized controlled trial, concluding that deferiprone monotherapy was superior to deferoxamine for improvement in RV EF and end-systolic volume. This improvement in the RV volumes and function may contribute to the improved cardiac outcomes seen with deferiprone.